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MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.

Nat Commun · 2015 · PMC4366510 · PMID 25743066

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The presence of Mir146a − / − B cells appeared to exacerbate the effect, but this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.