In a second cohort comprising 80 RA patients, [C5a] again showed strong positive correlation with risk allele number ( p < 0.001), and [C5] showed a trend to negative correlation that did not reach significance; as in healthy subjects ( Supplemental Fig. 1 ), [TCC] was not different between the groups (data not shown).
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Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis.
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