Although tumor-derived cells of HPV-positive tumors also expressed higher levels of proinflammatory cytokines, namely IL-2, IL-17, IL-23 and IFNγ, these differences did not reach statistical significance due to high variability in the samples.
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Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
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