Comparison of the anti-lysoganglioside-GM1 antibody titers of the six children at the five time points vs the combined control group’s median values (median titer of 320) showed that they were significantly different at the Post Exac 1 and 2 time points (p = 0.08/0.12/0.08/0.02/0.03, respectively) and the other 3 time points approached significance.
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Neuronal antibody biomarkers for Sydenham's chorea identify a new group of children with chronic recurrent episodic acute exacerbations of tic and obsessive compulsive symptoms following a streptococcal infection.
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