An 18 kDa scaffold protein is critical for Staphylococcus epidermidis biofilm formation.

Despite a slight trend towards lower catheter adherent bacterial counts in Sbp-negative mutants derived from S . epidermidis 1457-M10 and 1585, the observed differences compared to their Sbp producing parent strains did not reach statistical significance.

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There was a trend towards lower numbers of catheter-associated bacteria and higher bacterial numbers in the peri-catheter tissue in 1457-M10Δ sbp and 1457-M10Δ aap Δ sbp , however the values did not reach statistical significance when compared to 1457-M10 ( Fig. 10 ).

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