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Functional genomic analysis identifies indoxyl sulfate as a major, poorly dialyzable uremic toxin in end-stage renal disease.

PLoS One · 2015 · PMC4374671 · PMID 25811877

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While these differences between subjects with and without RRF did not reach statistical significance in this small sample, the gene array data shed some light on the importance of RRF in patients undergoing chronic dialysis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.