Barely Significant
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Molecular dynamics study of naturally existing cavity couplings in proteins.

PLoS One · 2015 · PMC4376744 · PMID 25816327

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a clear trendno p-value reported
However, we could not see a clear trend relating sequence changes and CSC survival/loss.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.