Preliminary investigation of miRNA expression in individuals at high familial risk of bipolar disorder.

3.3 Identification of differentially expressed miRNAs Of the sixteen reliably detected miRNAs, three, miR-15b, miR-132, and miR-652, showed a nominally significant increase in expression in the high-risk subjects compared to the control subjects (miR-15b: p = 0.0166, fold-change (FC) = 1.29; miR-132: p = 0.0249, FC = 1.34; miR-652: p = 0.0108, FC = 1.26; Fig. 1 ; Table 2 ).

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