Changes in insulin receptor signaling underlie neoadjuvant metformin administration in breast cancer: a prospective window of opportunity neoadjuvant study.

Breast Cancer Res · 2015 · PMC4381495 · PMID 25849721

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approached significanceno p-value reported

A decrease in insulin levels approached significance and was likely due to the small sample size (n = 39) and short duration of metformin treatment.

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