Regular inhaled corticosteroids in adult-onset asthma and the risk for future cancer: a population-based cohort study with proper person-time analysis.

5 Subsequently, a small, randomized, placebo-controlled, Phase IIb clinical study suggested that inhaled budesonide decreases the proportion of lung nodules in smokers with bronchial dysplasia as detected by spiral computerized tomography ( P =0.024); 6 a second randomized, placebo-controlled, Phase IIb clinical study showed a trend toward regression of ground glass opacities. 6 , 7 The cancer prevention property of ICS has been addressed in COPD populations in the following three clinical studies.

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