The genetic architecture of gene expression levels in wild baboons.

Elife · 2015 · PMC4383332 · PMID 25714927

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 10 −280actually significant

Consistent with this idea, plotting eQTL effect size vs MAF in the baboons results in a very strong, highly significant negative correlation (r = −0.723, p < 10 −280 ; Figure 3C ), with no large effect eQTL detected at higher MAFs.

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nominally significantp = 0.002actually significant

The correlation between a gene’s average phyloP score (from the 46-way primate comparison) and the average MAF of all SNPs tested in association with that gene is nominally significant (p = 0.002) but explains a very small fraction of the variance (r = -0.037).

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