Also, at week 12, the differences in mean blood flow did not reach statistical significance, indicating no significant anti-fibro-proliferative effect of ambrisentan either, in the given time frame of three months.
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Evaluation of the effect of ambrisentan on digital microvascular flow in patients with systemic sclerosis using laser Doppler perfusion imaging: a 12-week randomized double-blind placebo controlled trial.
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