The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding.

Oncotarget · 2015 · PMC4385857 · PMID 25544774

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did not reach statistical significanceno p-value reported

Though differences did not reach statistical significance in all instances, the failure to block ASML-CD151/Tspan8 kd exosome adhesion by either anti-CD49c or anti-CD104 confirms the importance of the tetraspanin-associated integrins in exosome targeting (Fig. 2G ).

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