Increased fiber size was also observed in the EDL, but presumably due to the lower AAV9 transduction efficiency, this did not reach statistical significance (p = 0.16) since all fibers in muscle cross-sections were measured in order to make sense of subsequent muscle force measurements in the EDL.
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Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia.
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0.1600
0.1600
The sentences
Provided this holds true for even a small subset of the downregulated targets, the impact of their downregulation could be highly significant to the progression of cancer-induced wasting and weakness.