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Quantitative measurement of HER2 expression in breast cancers: comparison with 'real-world' routine HER2 testing in a multicenter Collaborative Biomarker Study and correlation with overall survival.

Breast Cancer Res · 2015 · PMC4391602 · PMID 25886996

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showed a trendP = 0.10so close (0.05 < p ≤ 0.1)
OS for local IHC equivocal (IHC 2+) was similar to that of local IHC positive (Figure 2 A: HR = 1.0; 95% CI, 0.43 to 2.6; P = 0.92) and showed a trend of shorter OS compared with local IHC negative (HR = 2.7; 95% CI, 0.82 to 9.2; P = 0.10).

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