Estrogens increase expression of bone morphogenetic protein 8b in brown adipose tissue of mice.

Biol Sex Differ · 2015 · PMC4392498 · PMID 25866617

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failed to reach statistical significanceno p-value reported

As reported before for the 3 T3-L1 pre-adipocyte cell line [ 27 ], DES induced the expression of the gene encoding the lipogenic transcription factor proliferator-activated receptor gamma (PPARγ) by 45%, although this failed to reach statistical significance.

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failed to reach significanceno p-value reported

Sham-operated female mice had lower BAT Fgf1 expression than sham-operated male mice and ovariectomy tended to increase BAT Fgf1 expression; however, this failed to reach significance.

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