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The relationship of serum macrophage inhibitory cytokine-1 levels with gray matter volumes in community-dwelling older individuals.

PLoS One · 2015 · PMC4395016 · PMID 25867953

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Since the mediation effects would not exist if the relationships between the independent variable (MIC-1/GDF15 serum levels in our case) and the possible mediator (GM volumes) did not reach statistical significance, we only tested the potential mediation effects for the GM regions with statistically significant associations with MIC-1/GDF15 ( Table 6 ).

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