Inflammatory mediator release from primary rhesus microglia in response to Borrelia burgdorferi results from the activation of several receptors and pathways.

J Neuroinflammation · 2015 · PMC4396743 · PMID 25889406

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showed a trendno p-value reported

Since NOD2 siRNA showed a trend in increasing the production of inflammatory mediators, with both the bacterium and the positive control, we wanted to confirm the efficacy of this treatment.

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an increasing trendno p-value reported

The production of IL-6 and CXCL8 also showed an increasing trend when CLI-095 was used in the presence of B. burgdorferi although not statistically significant in a majority of experiments.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.