Barely Significant
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Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins.

PLoS One · 2015 · PMC4400099 · PMID 25880638

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hedged sentence
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closest p · 1.8× alpha
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boldest claim

The sentences

showed a trendP = 0.09so close (0.05 < p ≤ 0.1)
Under fasting conditions, WT mice had lower levels ( P < 0.05) of F2,6BP than their fed counterparts while the ShcKO mice showed a trend ( P = 0.09) toward a decrease in F2,6BP with fasting.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.