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Cancer spectrum and frequency among children with Noonan, Costello, and cardio-facio-cutaneous syndromes.

Br J Cancer · 2015 · PMC4402457 · PMID 25742478

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In agreement with previous case reports, our data suggested an association between PTPN11 germline mutations and ALL (Observed=2, SIR=7.1, 95% CI=0.9–25.6), which did not reach statistical significance.

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