As regarding the relation between 1 HMRS and EEG, we found that there was a significant negative correlation between IEDs and NAA/Cr ratio and these results were concordant with most of the previous studies as; Garcia and colleagues [ 18 ] studied 16 patients with temporal lobe epilepsy by EEG and 1 HMRS and they found that decreasing NAA correlated with increased spike frequency, and Sarles and colleagues [ 19 ] studied 14 patients with frontal and temporal lobe epilepsy and they found that there was an overall trend in which spike frequency and NAA/Cr ratio were correlated inversely, although the results did not reach statistical significance, the trend was obvious.
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Childhood temporal lobe epilepsy: correlation between electroencephalography and magnetic resonance spectroscopy: a case-control study.
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found that decreasing NAA correlated with increased spike frequency, and Sarles and colleagues [ 19 ] studied 14 patients with frontal and temporal lobe epilepsy and they found that there was an overall trend in which spike frequency and NAA/Cr ratio were correlated inversely, although the results did not reach statistical significance, the trend was obvious.