Evidence of Aortopathy in Mice with Haploinsufficiency of <i>Notch1</i> in <i>Nos3</i>-Null Background.

In the aorta, MMP2 expression was found to be increased in Notch1 +/− ; Nos3 −/− , and the Notch1 +/− ; Nos3 −/− aortas in comparison to wildtype littermates although it did not reach statistical significance ( Figure 5 A–D).

also in 111,027 other papers