By contrast, 3’SS in general did not appear to play a major role in intronic C/P in the samples analyzed in this study, except for some modest significance for the last introns containing upregulated pAs by siSF3b155 and siU2AF65 ( Fig 3D ).
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Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation.
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