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Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion.

Am J Reprod Immunol · 2015 · PMC4409084 · PMID 25469631

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2 d shows that pre-treatment with the TLR4 inhibitor CLI-095 abrogated the increased TRIF mRNA expression seen in HTR-8 cells treated with VT−/PM+ IgG, although this difference failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.