Intrathecal injection of lentivirus-mediated glial cell line-derived neurotrophic factor RNA interference relieves bone cancer-induced pain in rats.

Cancer Sci · 2015 · PMC4409887 · PMID 25611164

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showed a trendno p-value reported

Although Lvs-siGDNF treatment showed a trend in the increase in mechanical PWT similar to the significant effect of the morphine-treated group (morphine vs normal, Nor+Lvs-siGDNF, control, and saline group, P = 0.026, 0.000, 0.000, and 0.000, respectively), no statistical significance between Lvs-siGDNF and NC-treated groups was found on day 7 after treatment.

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