We examined expression of FGFR2 in each tumor group and found that Fgfr2 expression tended to be higher in Sox2-Lkb1 tumors compared to Kras G12D Lkb1 fl/fl squamous tumors, but these data did not reach statistical significance ( Figures 3A and 3B ).
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Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.
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