Evaluating the SERCA2 and VEGF mRNAs as Potential Molecular Biomarkers of the Onset and Progression in Huntington's Disease.

PLoS One · 2015 · PMC4411078 · PMID 25915065

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hedged sentences

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

highly significantp<0.01actually significant

As shown in Fig 2A , all the HD-affected patients and even all the pre-manifest subjects displayed a highly significant reduction in SERCA2 mRNA, ranging from p<0.01 and p<0.001, compared with the control mRNA levels.

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did not reach statistical significanceno p-value reported

However, the reduction of SERCA2 mRNA in the manifest versus pre-manifest subjects did not reach statistical significance.

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