While the pD 2 of Ach in xyl-B treated apoE −/− mice (−7.12 ± 0.04) tended to increase, it did not reach statistical significance as that in the Simvastatin group (−7.38 ± 0.04) in comparison to apoE −/− mice (−6.94 ± 0.02).
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Xyloketal B attenuates atherosclerotic plaque formation and endothelial dysfunction in apolipoprotein e deficient mice.
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