AS03-Adjuvanted, Very-Low-Dose Influenza Vaccines Induce Distinctive Immune Responses Compared to Unadjuvanted High-Dose Vaccines in BALB/c Mice.

Front Immunol · 2015 · PMC4413846 · PMID 25972874

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did not reach statistical significanceno p-value reported

Surprisingly, the unadjuvanted low-dose vaccine tended to induce the highest level of IL-12, a Th1-promoting cytokine, although this difference did not reach statistical significance.

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