Acute and chronic effects of lithium on BDNF and GDNF mRNA and protein levels in rat primary neuronal, astroglial and neuroastroglia cultures.

Iran J Basic Med Sci · 2015 · PMC4414989 · PMID 25945236

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did not reach statistical significanceP >0.05actually significant

Acute lithium treatment reduced GDNF mRNA levels in mixed neuro-astroglial and astrocyte cultures by the factor of 1.69±053 and 1.04±0.39, respectively, in comparison with vehicle treated cultures ( Figure 1b ), but these changes did not reach statistical significance ( P >0.05).

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