Germline MUTYH gene mutations are not frequently found in unselected patients with papillary breast carcinoma.

found that minor allele genotypes of several MUTYH variants showed a trend towards association with lobular BC histology [ 14 ], while Rennert et al . found no differences for ductal or other BC histology type among 30 patients heterozygous for p.Gly396Asp or p.Tyr179Cys and 359 patients homozygous wild-type for these mutations [ 15 ].

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