Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators.

PLoS One · 2015 · PMC4418712 · PMID 25938230

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did not reach statistical significanceno p-value reported

P-cresol sulfate had a linear increase in risk below the 75 th percentile (HR PerSD , 2.57; 95% CI, 1.19–4.75; p = 0.003) with attenuation of the hazard above this level although the change in slope did not reach statistical significance (p-value for change in slope = 0.13; S5 Table ).

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