A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality.

The proportion of IL-18Rα + CD4 + T cells that were BrdU + increased after the addition of TL1a or IL-15 to IL-12/IL-18 cultures, although the former did not reach statistical significance ( Figure 3g ), and this was further increased after the addition of both TL1a and IL-15 ( Figure 3g ).

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