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Studying cerebral hemodynamics and metabolism using simultaneous near-infrared spectroscopy and transcranial Doppler ultrasound: a hyperventilation and caffeine study.

Physiol Rep · 2015 · PMC4425980 · PMID 25907789

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showed a trendno p-value reported
As the placebo group showed a trend in the fdNIRS data over the 60 min of the study, we also undertook a doubly repeated analysis of covariance to take into account the effect of the placebo condition.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.