nominally significantp = 0.02
I could only find one cancer type (GBM) where mutations in TP53 are associated with a nominally significant increased age acceleration (p = 0.02)". as follows: TP53 mutation is associated with significantly lower age acceleration in six data sets (Additional file 6 ) including AML (P = 0.0041), breast cancer (P = 7.8×10 −12 and P = 1.4×10 −12 ), ovarian cancer (P = 0.04), uterine corpus endometrioid (P = 0.0012), and colorectal cancer (P = 0.036, Figure 4 B).