Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington's disease following transplantation of bone-marrow-derived mesenchymal stem cells is dependent on passage number.

Stem Cell Res Ther · 2015 · PMC4429666 · PMID 25971780

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a strong trendno p-value reported

Analysis of expression levels of the BDNF receptor TrkB revealed no significant differences between groups ( F (3,15) = 1.895, P = 0.184; Figure 8 B), although a strong trend was observed between WT and R6/2 mice.

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