Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive.

Conversely, Type 1 regulatory T (Tr1) cells, which co-express CD223 and CD49b ( Fig 3A , right panel), were slightly increased in 4x compared to 1x DEC as a proportion ( Fig 3B , p<0.05), but the difference in the total number of Tr1 cells between the infection groups did not reach statistical significance ( Fig 3C , p>0.05).

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