The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains.

Sci Rep · 2015 · PMC4434891 · PMID 25984708

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difference was apparentno p-value reported

However, a clear difference was apparent with regards to the nature of the protein-DNA complex observed in the gel after interaction of HM and HL fragments with ssDNA.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.