Daclizumab reverses intrathecal immune cell abnormalities in multiple sclerosis.

Ann Clin Transl Neurol · 2015 · PMC4435700 · PMID 26000318

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a nonsignificant trendno p-value reported

We observed a nonsignificant trend toward increased CD4/CD8 ratios in untreated RRMS patients, which was completely normalized within (but not below) physiological (HD) range in Dac-HYP cohort.

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did not reach statistical significanceno p-value reported

While similar trends were observed for LTi cells (enumerated in this study as c-kit+ ILCs), they did not reach statistical significance in the blood due to a single HD outlier.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.