showed a trendP = 0.13
To this end, OS cells were shown to express several components of the WNT signaling pathway and the chemotactic response to exogenous WNT was increased in a mouse metastatic OS cell line compared to the parental cells with low metastatic potential, and increased WNT10B expression showed a trend (n = 44; P = 0.13) to shorter survival in patients [ 45 , 46 ].