Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System.

Direct measurements of proteasome activity in MIN6 cells showed a trend towards decreased activity after palmitate exposure ( Figure 2(d) ) and a marked reduction in activity after treatment with the synthetic proteasome inhibitor MG132 ( Figure 2(e) ).

also in 53,322 other papers