Unbalanced Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinases Ratios Predict Hemorrhagic Transformation of Lesion in Ischemic Stroke Patients Treated with Thrombolysis: Results from the MAGIC Study.

Front Neurol · 2015 · PMC4445323 · PMID 26074872

Europe PMC DOI

hedged sentences

0.0040

closest p · 0.1× alpha

0.0070

boldest claim

The sentences

showed a trendp = 0.004actually significant

At univariate analysis, only relative increase in MMP9/TIMP2 ratio proved significantly associated with sICH, while MMP9/TIMP1 ratio showed a trend toward significance ( p = 0.004, p = 0.018, respectively).

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a trend toward significancep = 0.007actually significant

Only relative increase in MMP9/TIMP1 ratio proved significantly associated with relevant HT (odds ratio [95% confidence interval], 1.74 [1.17–2.57], p = 0.006) with a trend toward significance for MMP9/TIMP2 ratio ( p = 0.007).

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