22 Although the difference in diurnal IOP between the study arms did not reach statistical significance (17.4 mmHg versus 18.3 mmHg from untreated baseline values of 24.9 mmHg and 24.7 mmHg, respectively), the IOP decrease in the morning was significantly greater, both statistically and clinically, with latanoprost therapy (−8.5 mmHg versus −6.0 mmHg).
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