Barely Significant
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Continuous metabolic monitoring based on multi-analyte biomarkers to predict exhaustion.

Sci Rep · 2015 · PMC4450587 · PMID 26028477

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showed a trendno p-value reported
Interestingly, glucose and lactate showed a trend change around 45 minutes into the exercise, 12 minutes before the first physical evidence of exhaustion and 42 minutes before full exhaustion (indicated by red ovals).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.