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Anti-tumor effects of metformin in animal models of hepatocellular carcinoma: a systematic review and meta-analysis.

PLoS One · 2015 · PMC4451077 · PMID 26030161

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showed a trendno p-value reported
Only two studies showed a significant decrease of HCC incidence; whereas the others showed trend of decrease but one showed a trend of increase.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.