Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition.

BMC Cancer · 2015 · PMC4453293 · PMID 25994202

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a clear trendno p-value reported

There was no statistically significant difference in the tumor growth inhibition observed between the two dosing sequences, but there was a clear trend suggesting that the ATA sequence yielded greater antitumor activity compared with TAA, with TGI increased by 19%.

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