Pharmacokinetics of concomitant cisplatin and paclitaxel administered by hyperthermic intraperitoneal chemotherapy to patients with peritoneal carcinomatosis from epithelial ovarian cancer.

Although the present study was performed on a limited number of patients, some of which were previously treated, and therefore it is difficult to draw conclusions on the toxicity, nevertheless it appears that the morbidity was quite significant and a high rate of hematological toxicity was observed as previously reported in other studies ( Coccolini et al , 2013b ).

also in 5,695 other papers