Results Aging phenotype Echocardiographic analysis showed thinner ventricular wall and a trend toward increased LV end-diastolic volume in old mice, as well as a nonsignificant trend toward reduced ejection fraction ( Table 1 ).
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Defective sarcoplasmic reticulum-mitochondria calcium exchange in aged mouse myocardium.
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The oxidized fraction of GSH (glutathione disulfide, GSSG) showed a trend toward an increase in the aging myocardium ( Figure 4e , left panel).