A common variant near TGFBR3 is associated with primary open angle glaucoma.

Hum Mol Genet · 2015 · PMC4459396 · PMID 25861811

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0.0200

closest p · 0.4× alpha

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nominally significantP = 0.02actually significant

One other marker ( FNDC3B rs4894796) was nominally significant in the replication stage (OR = 0.95, P = 0.02) and remained suggestively associated with POAG in the overall meta-analysis (OR = 0.93, P = 1.40 × 10 −5 ) (Fig. 1 C; Supplementary Material, Table S2 ).

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