Exercise intolerance in heart failure with preserved ejection fraction: more than a heart problem.

J Geriatr Cardiol · 2015 · PMC4460174 · PMID 26089855

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[103] Compared to valsartan alone, the LCZ696 (Neprilysin, the zinc-dependent metalloprotease that degrades biologically active natriuretic peptides) group had significantly lower NT-pro BNP levels and at 36 weeks, decreased LA size and showed a trend toward improved functional class in PARAMOUNT study.

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